The more prevalent Denuvo gets, the easier it will to analyze its working, though. Even if it might not produce a method to crack games in any interesting time frame, it could be used to circumvent it years down the line.
I say this, because as far as I understand, their strongest asset currently is the fact that no one seems to understand how exactly it works, only basic principles. In cryptographic terms, the best systems provide security by assuming the attacker knows everything but the (private) key and even then you can always bruteforce a key by going through all possibilites (and use intercepted encrypted messages, which is not the same as "breaking" it). I'm sure the same holds for Denuvo, assuming they even use cryptographic methods.