Ozempic. Does it work?

Semaglutide should not be an easy way out for those who can still turn their lifestyle around, of course.
It's a diabetes drug first and foremost.
That said, there's a lot of people who are way beyond the point of no return regarding obesity, and for which surgery is not an option due to age or other complications already induced by obesity (joint damage, cardiovascular strain, atherosclerosis, thrombotic risk, etc). Ozempic/Mounjaro should definitely be a stepping stone for them. And those drugs should always be accompanied by a custom dieting and exercising program anyway.
 
I don't know because I haven't tried it (nor want/need) but the mechanism of action restricts your hunger by slowing digestion. That, to me, sounds horrifying, slow motility is an issue for a lot of people.

OP if you want to lose weight it is very (very easy). Cut sugary shit as much as possible and walk, that's really it. If you want to lose faster walk right after you wake up (your glycogen levels are low and the body will have no other choice than to mobilize and metabolize fat).
 
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I've never used it but it definitely works. With GLP-1s we may cure rampant obesity in America within a decade or so. They definitely have side effects though from what I've heard from people who take them. Diarrhea, vomiting, among other things. The ideal way to lose weight is diet, exercise, lifestyle changes, but the reality is many can't or won't do it, so these drugs have been wonders for people.
 
Article:
An analysis by University Hospitals Cleveland Medical Center of records from the TriNetX database found that the number of patients diagnosed with gastroparesis after being prescribed a GLP-1 receptor agonist (0.1% of the patients) was 250% greater than the number of patients diagnosed with gastroparesis who did not take a GLP-1 medication (0.04%).[28]

Oh. That might be a problem.

Well, that's partially how it works. GLP-1 is supposed to slow stomach emptying and promoting satiety. It's like taking a blood thinner - you expect the side effect of increased risk of bleeding.
 
The way to think about these drugs is like insulin, something a broken body doesn't do well enough. For whatever reason, some people have poor activation of GLP-1 and GIP signalling, which makes them hungry, fat, causes poor blood values, inflammation. The drug gets them back to a healthy level.
 
All the fat people will get back to being fat the moment they stop taking the drug. This is not a cure, healthy living and better quality food is.
Well that's a lost cause. Whatever you want to call it, I believe obesity rates in America will plummet over the next decade. Whether that qualifies as a cure, as a fool's gold, as a band-aid, as a patch, whatever it is, I consider that a good thing. Don't let the perfect become the enemy of the good. I think we should embrace lower obesity numbers any way we can get them.
 
All the fat people will get back to being fat the moment they stop taking the drug. This is not a cure, healthy living and better quality food is.
A lot of times they go back, but there are people whose mentals become stronger after they've lost the weight and learn how to keep it off, because those types were miserable and didn't know a way out of their situation at the time. Learning from your mistakes should be easy and something repeatable. I don't talk down on people who don't, because I used to be one, myself. Now, I am willing and ready to learn, at all times. Observe, rather than come up with an answer to any/everything, right away.
 
Well that's a lost cause. Whatever you want to call it, I believe obesity rates in America will plummet over the next decade. Whether that qualifies as a cure, as a fool's gold, as a band-aid, as a patch, whatever it is, I consider that a good thing. Don't let the perfect become the enemy of the good. I think we should embrace lower obesity numbers any way we can get them.
I mean - if they will keep the weight, kudos to them. I just think in the past few decades we have a lot more education about physical health, numerous initiatives to improve food quality and people get fatter. I think instead of the drug (again if it works - great, I just don't think it will) we should be looking at health education, and most importantly - taxing the shit out of bad food. You will mysteriously notice when companies have money on the line they will suddenly figure out how to make their food healthier.
 
I'm not on Ozempic -- but Mounjaro -- and yeah, I can say it definitely works. Me personally, I've had no side effects, and on average I've been losing about a pound of week.

It's a helpful tool, but if you want to ever stop taking it - you've gotta make all the smart lifestyle changes too.
 
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