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[NeoIkaruGAF]

Semaglutide should not be an easy way out for those who can still turn their lifestyle around, of course.
It's a diabetes drug first and foremost.
That said, there's a lot of people who are way beyond the point of no return regarding obesity, and for which surgery is not an option due to age or other complications already induced by obesity (joint damage, cardiovascular strain, atherosclerosis, thrombotic risk, etc). Ozempic/Mounjaro should definitely be a stepping stone for them. And those drugs should always be accompanied by a custom dieting and exercising program anyway.

 

[T-0800]

Giving sugary drinks is nothing else than giving up smoking - your brain craves it so it will fight you.

Sure. For a few days.

 

[Cyberpunkd]

Sure. For a few days.

Well yeah, the point is to survive those few day and not give up. Although when I gave up alcohol cold turkey my doctor was worried it's too sudden

 

[thefool]

I don't know because I haven't tried it (nor want/need) but the mechanism of action restricts your hunger by slowing digestion. That, to me, sounds horrifying, slow motility is an issue for a lot of people.

OP if you want to lose weight it is very (very easy). Cut sugary shit as much as possible and walk, that's really it. If you want to lose faster walk right after you wake up (your glycogen levels are low and the body will have no other choice than to mobilize and metabolize fat).

 

[Porcile]

It makes people look like they have cancer.

 

[Avid Reading Horse]

 

[DragoonKain]

I've never used it but it definitely works. With GLP-1s we may cure rampant obesity in America within a decade or so. They definitely have side effects though from what I've heard from people who take them. Diarrhea, vomiting, among other things. The ideal way to lose weight is diet, exercise, lifestyle changes, but the reality is many can't or won't do it, so these drugs have been wonders for people.

 

[Dr.Guru of Peru]

Article:

An analysis by University Hospitals Cleveland Medical Center of records from the TriNetX database found that the number of patients diagnosed with gastroparesis after being prescribed a GLP-1 receptor agonist (0.1% of the patients) was 250% greater than the number of patients diagnosed with gastroparesis who did not take a GLP-1 medication (0.04%).[28]

Source: https://en.wikipedia.org/wiki/Gastroparesis

Oh. That might be a problem.

Well, that's partially how it works. GLP-1 is supposed to slow stomach emptying and promoting satiety. It's like taking a blood thinner - you expect the side effect of increased risk of bleeding.

 

[Chittagong]

The way to think about these drugs is like insulin, something a broken body doesn't do well enough. For whatever reason, some people have poor activation of GLP-1 and GIP signalling, which makes them hungry, fat, causes poor blood values, inflammation. The drug gets them back to a healthy level.

 

[Cyberpunkd]

With GLP-1s we may cure rampant obesity in America within a decade or so.

All the fat people will get back to being fat the moment they stop taking the drug. This is not a cure, healthy living and better quality food is.

 

[DragoonKain]

All the fat people will get back to being fat the moment they stop taking the drug. This is not a cure, healthy living and better quality food is.

Well that's a lost cause. Whatever you want to call it, I believe obesity rates in America will plummet over the next decade. Whether that qualifies as a cure, as a fool's gold, as a band-aid, as a patch, whatever it is, I consider that a good thing. Don't let the perfect become the enemy of the good. I think we should embrace lower obesity numbers any way we can get them.

 

[Dirk Benedict]

All the fat people will get back to being fat the moment they stop taking the drug. This is not a cure, healthy living and better quality food is.

A lot of times they go back, but there are people whose mentals become stronger after they've lost the weight and learn how to keep it off, because those types were miserable and didn't know a way out of their situation at the time. Learning from your mistakes should be easy and something repeatable. I don't talk down on people who don't, because I used to be one, myself. Now, I am willing and ready to learn, at all times. Observe, rather than come up with an answer to any/everything, right away.

 

[Cyberpunkd]

Well that's a lost cause. Whatever you want to call it, I believe obesity rates in America will plummet over the next decade. Whether that qualifies as a cure, as a fool's gold, as a band-aid, as a patch, whatever it is, I consider that a good thing. Don't let the perfect become the enemy of the good. I think we should embrace lower obesity numbers any way we can get them.

I mean - if they will keep the weight, kudos to them. I just think in the past few decades we have a lot more education about physical health, numerous initiatives to improve food quality and people get fatter. I think instead of the drug (again if it works - great, I just don't think it will) we should be looking at health education, and most importantly - taxing the shit out of bad food. You will mysteriously notice when companies have money on the line they will suddenly figure out how to make their food healthier.

 

[RavenSan]

I'm not on Ozempic -- but Mounjaro -- and yeah, I can say it definitely works. Me personally, I've had no side effects, and on average I've been losing about a pound of week.

It's a helpful tool, but if you want to ever stop taking it - you've gotta make all the smart lifestyle changes too.

 

[Chittagong]

 

[Dr.Guru of Peru]

Yeah, that white ceramic lake tahoe is sexy. What does this have to do with ozempic?

 

[Gp1]

There's this new peptide that's in the testing phase in the FDA that is apparently better with little to no side effects. If you're set on taking Ozempic, it might be better to go for that instead. Results come out on 2026 iirc.

I personally did it the old fashioned way. It does take some discipline and time though. That's usually the issue that comes up when I ask people who want to lose weight. No time for cardio, meal preps or healthy alternatives are more expensive.

Retratutide. It's the new get go drug even for body builders. Its on phase 3 clinical trials now and is expected to be FDA approved by 2027.

If I were to start losing weight now, I would try the traditional way first (nutritionist, personal trainer, endocrinologist, etc). If you succeed... better. If not, you'll probably have a much more effective drug available by the time you fail

Giving sugary drinks is nothing else than giving up smoking - your brain craves it so it will fight you.

Switch to zero sugar for a while, then to pulp juice (at least were i live it's dirt cheap and have practically zero calories) with stevia, lemon and carbonated water. Infinitely better than sugary drinks. Plus near zero/zero calories.

 

[Dr.Guru of Peru]

Retratutide. It's the new get go drug even for body builders. Its on phase 3 clinical trials now and is expected to be FDA approved by 2027.

If I were to start losing weight now, I would try the traditional way first (nutritionist, personal trainer, endocrinologist, etc). If you succeed... better. If not, you'll probably have a much more effective drug available by the time you fail

Wild at the amount of money that's getting spent on finding ways to prevent people from essentially just not stuffing their face with nachos. I get the public health importance of tackling the obesity crisis, but when you step back and look at first principles its just seems like a needlessly sophisticated solution to a simple problem. This reminds a lot of the framing pharmaceutical companies provided with SSRIs, arguing that mood disorders represented a "chemical imbalance" when in reality the drugs have never been proven to be more effective than structured behavioral therapy.

 

[Cyberpunkd]

Yeah, that white ceramic lake tahoe is sexy.

If someone likes a washed out brand that released hundreds of limited editions in 2010s. Which is a shame because my late grandfathers wish was to own an IWC one day. They also obviously paid for product placement, given that Sheeran is a hardcore PP guy.

 

[Gp1]

Wild at the amount of money that's getting spent on finding ways to prevent people from essentially just not stuffing their face with nachos. I get the public health importance of tackling the obesity crisis, but when you step back and look at first principles its just seems like a needlessly sophisticated solution to a simple problem. This reminds a lot of the framing pharmaceutical companies provided with SSRIs, arguing that mood disorders represented a "chemical imbalance" when in reality the drugs have never been proven to be more effective than structured behavioral therapy.

It's easier to just stuff yourself with nachos than (IF you are a normal healthy person, without any medical alteration):

Undo years of food emotional attachment +
Plan your dietary needs to know how many calories you have to eat +
Buy your healthy food while being bombarded with "nacho like" hyperpalatables everywhere +
Cook for an entire week (and maybe cook for your entire family) +
Partition your food for every meal, and find time to do everything above while having your daily routine +
Pull your healthy lunchbox while everyone is feasting on nachos around you.

The solution is very simple and known but it takes a lot of discipline. In broader terms you just have to burn more calories than you ingest, while trying to create muscle by weightlifting and consuming a fair share of protein.

The problem lies on the execution.

Its way easier for to just take a shot and see the results fast because you simply don't fell hungry than do everything i wrote, although you still need to change your life style. (considering that the person even has the knowledge about it)

Plus with Retratutide you even has the benefit that it accelerate your metabolism so you don't lose too much muscle while losing weight (no more Ozempic head).

 

[NeoIkaruGAF]

With GLP-1s we may cure rampant obesity in America within a decade or so.

Unless your weekly shot costs less than a McD burger, this won't happen.
The people who need these drugs the most are also probably those who can't afford it.
Even countries with universal health care give these drugs only to diabetics. Obese people who don't have diabetes must pay for the drugs in full, and in the current economy, it's a price not many people can afford.

 

[Come On Tars]

Yeah, that white ceramic lake tahoe is sexy. What does this have to do with ozempic?

As someone from Lake Tahoe what are you talking about. I'm searching for a tattoo.

edit nvm it's the watch.

 

[The Skull]

I've had 3 friends take Mounjaro and they've all came off it. One ended up in hospital with kidney issues, the other wouldn't stop having what we called "Godzilla burps" which smelt like vomit that was on fire and the other started collapsing regularly. That being said I've known people that have taken it without issue so it certainly seems to be luck of the drawer when it comes to side effects.

One of the guys is now on retatrutide and is doing much better. He was around 620 pounds but is now down to about 500.

As most others have probably pointed out though, if you don't fix the underlying issue that caused you to be in that situation the first place, you'll bounce back once you come off it. Fixing your relationship with food and having a more active lifestyle should be the number one priority.

 

[L*][*N*K]

Yes it does, I share an office with someone who was around 134kgs in January he was prescribed Ozempics at a low dose (0.5mg) and he is actually losing alot more weight that I thought he would, but it motivated him to start eating healthier and workout more which definitely pushed it really forward positively, Idk where he will be at in a year but what I see is an impressive result

 

[Trilobit]

Found out today that my brother who is obese and his wife have been taking it for a couple months now, after my mother told me he has been sickly and lathargic lately. When asked he said its normal when starting off, then the symptoms will go away. Even though I could benefit from losing some kgs myself I'm dubious of anything that is sold as a magic pill.

Any personal experience? Long term side effects?

Doesn't it just make you eat less, by stifling hunger?

You know what a cheaper drug-less method would be? Become so poor that you can't afford to eat for more than $50 in a month. You'll be forced to eat less, make sure the dishes are as nutritious as possible and that most ingrendients are whole foods, like beans, lentils, eggs etc. The less you eat the less calories you'll put around your waist.

You won't even need to exercise to burn off fat.

Sure. For a few days.

Quitting sugar completely can take a lot longer. The first time I tried to quit it took a year actually. If you're depressed etc. and lack good habits(because of reasons), then it'll be like cutting off one of few joys in life. And the body and mind will scream after it. Some people can quit cold turkey, but others like me, will need longer to make it sustainable.

It's better to think about it longterm, by cutting off sugar step by step. Go from eating every day to only Saturdays. Then from there to only rarely. And then to almost nothing, no sweets, candy, sodas etc. That way you have time to acclimatize your body and psyche and you can replace bad eating habits with good ones. In the end you'll not even crave sugar.

 

[DirtInUrEye]

Sheeran is in porn now?

 

[Davevil]

 

[Coloress_Kafka]

I took it for 6 months and only lost 5lbs so I stopped. BIG MISTAKE I gained 40lbs within a few months.

I started taking it again but I also asked my doctor to put me on Wellbutrin and that combo worked out fantastic. The semaglutide helps keep me from over eating and the Wellbutrin gave me the energy and confidence to hit the gym on a regular basis. Im now down 60 lbs and sitting at 199. Goal is to hit normal BMI which for my height is 183.

 

[jason10mm]

All the fat people will get back to being fat the moment they stop taking the drug. This is not a cure, healthy living and better quality food is.

I agree with you, which is why we ALSO need government to stop paying for shit food/sugar water via food stamps, aggressively educate on better eating habits, penalize companies growing crap versions of wheat and corn, and completely disengage with any company selling HFCS and sugar rich crap.

We live in a dietary cesspool that makes it too easy to be fat. And now we have decades of shit nutritional advice (avoid butter, eggs, limit meat, use these seed oils and chemically treated wheat flour instead!) we have to try to roll back so folks can understand that a twinkie should be viewed more like a cigarette (i.e. a dangerous indulgence) rather than a common, albeit tasty, snack.