I've been playing BotW for the last month or so on CEMU and it's such a better experience. I've beaten BotW on Wii U and Switch and the CEMU version is miles ahead. 3440x1440 75+fps. Such a better experience. Using the Pro controller and gyro for aiming too. Use CEMU though, it has WAY more options for BotW and runs it WAY better than the Switch Emulator(Yuzu).
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I too get BotW vibes from Biomutant and have had my eye on it for a very long time. I really like what I've seen. If they can nail that sense of exploration from BotW while making the combat more exciting and engaging, they could have a big hit on there hands. I'm not completely sold on some of the footage I've seen of the combat, but that could boil down to me just not liking the way the person is choosing to play. Only a few more days until we know more.