I hate the way they handle auto-saves. I got to what I thought was an auto-save spot, just had a big gun fight, followed by a cut-scene, and entered a new area.. Now you'd think that would be enough. But nope.. Save anywhere is cheap, and would probably hurt this game. However, they could've made the game save more frequently.
I honestly had no problem with the save system until last night when I decided to get up and be social; instinctively brought up the menu to save, and realized I was boned.
At the very least, I wish they had come up with something similar to DS games, where you can save the game-state for a one-time-only reload.
Anyway, it's just one little complaint among a thousand things I really like about BI.