Regarding any possible twists: I hope it can live up to Bioshock's. And not in that, "Oh hey, this plot has changed dramatically" but in the "Holy shit this plot has now changed the way I look at myself." Bioshock was special, it made me feel things more strongly than I would in other medium because i was a participant. It shone a light on the things I was doing, it made me question the nature of choice in games, and less so about choices in my own life. It legitimately pushed games narrative forward.
That's the thing I worry Infinite won't hit, that place where the narrative rises above what could be done with a standard narrative. I mean, the world looks cool, the themes are topical and look like they are handled deftly. I wonder though, can it push ludo narrative again, and can it make points about something wider than on the nature of games?
If it doesn't, It's looking like a really good RPG shooter, with an interesting story, but I'm not sure yet if it will be something important like the first bioshock was.