Oh fucking christ that sounds painful. I can deal with those separately, but in the same room? FUCK! I'd have to go after the maidens, run around the fucking room to space shit out, kill the other maiden, run around the room, stun lock kill a werewolf and then kill the other or something, that just sounds sadistic.
Yeah, I quit that dungeon right there, and haven't gone back yet. I guess I'll eventually try taking care of the maiden below first, because the werewolves are guarding the other above the stairs.
It was my least favorite room until I found another one. I forgot which chalice it is but this room had the witch of hemiwick and 4 of those enemies it spawns. Hemiwick Witches are incredibly annoying since they instantly spawn new enemies after you've killed them. When you rush her, she does a blasted aoe attack that either one shots you or knocks you down for her minions. At least you can funnel the spiders away from the maidens and the Maiden doesn't hit hard. Witch of Hemiwick can kiss my ass.
It is and the spiders are annoying with the range and space of their attacks. You'll find a solution once you encounter it.
I don't think I've come across a witch that spawns new enemies so far. IIRC, it was Isz Root chalice, where there was a room with two witches, one throwing fire and the other bolt projectiles, accompanied with Keeper of the Old Lords & two Hellhounds, and a werewolf. The hellhounds are far worse than the werewolves. The room was a pain the ass. I had to lure them away from there one by one, until only the witches remained. Even then, I had to kill one of them with Evelyn & Bone Marrow Ash, because the projectiles killed me with two hits, and they spammed them a handful at the time.
Worst room I've encountered is one in Isz where there were 2 aliens spamming their arcane projectile attacks from a distance.
Two Brainsuckers were guarding one of them, while up some stairs there were 3 lycans guarding the other. Then there were a couple more Brainsuckers sprinkled in somewhere in the room for good measure.
That was challenging/annoying room as well.