Best way to handle the brain trusts in hamlet?
Be prepared with sedatives, high frenzy resist armor/runes and use Ludwig two handed mode to take them out. Then you might have just enough time to use the sedative or alternatively if you have high enough health you can eat the frenzy while hacking at the second enemy. I've got it down to so that I can take them both out but only get hit by frenzy once.
I never got the parry timing on their grab quite right so I found the Ludwig sword was the faster and better option. Basically you want something that staggers them so they can't do the grab attack.