Well, those two injuries aren't that "bad", if Reus is back for the Zenit match. Großkreutz/Hofmann should be able to replace Reus against Frankfurt (cup), Frankfurt (league) and HSV. Kehl will do for Bender, too. And we might be able to see Jojic play earlier than expected.
But still, it's just ridiculous.
While Bender's injury is nothing rare, it is pretty clear the players are exhausted and that's why they are getting so many injuries. The same thing happened to Bayern in 10/11 after reaching CL final with a thin squad