Talking about lack of representation in media in general ... maybe even saying games.
Ways to revert, good examples and other stuff.
The site and the video in it already make a good point, although so a thread around it won't sound like complaining or be interpreted a such, enhancing the visibility of the media that does it right sounds like a possible strategy, like encouraging people to post favorite examples or interesting cases that might have slipped the attention of most, encouraging people to focus on the positive instead of presenting a negative some would feel compelled to counter.
Wasn't there a recent article somewhere about the studio that released the Hunger Games and Twilight movies made a lot more money than it would ever expect from stories with female leads? Sure, Twilight has issues (and I prefer Battle Royale to THG), but those are speaking a language the market undrstands, which sounds like a step forward, hopefully followed by more and better ones.
As "activism" goes by people not making more media themselves that would even the odds, the one thing that crosses my mind would be, when in doubt, to spend money on the media and merchandise that takes that kind of balanced attitude toward female protagonism - again, the language the market understands.
As for interesting gaming examples, I like the fun factoid that Namco's Baraduke (a.k.a. Alien Sector) had a female protagonist even before Metroid, while finding it odd that Namco has barely taken advantage of that historical landmark. The game had one sequel, the character back then has referred to as "Kissy", and was only given a real one, Tobi Masuyo, later in the Mr. Driller games as an NPC, as the protagonist's mother and ex-wife to Taizo Hori, a.k.a. DigDug. It took Namco X Capcom to make her playable again, and in the process she was included in Namco's larger
United Galactic Space Force (USGF) series. That USGF thing could be an interesting way to play to 2 aspects of gaming history and bring the character the relevance it deserves, but some awareness needs to be raised for that to happen. The project has
a Twitter account, maybe more people following it would help encourage Namco do to something with the concept and its characters.
Another personal favorite case is Streets of Rage 2 - while it falls to many trapping of its genre, it's the only beat-em-up I know where the all-rounder character is female, as one can see in the select screen's stats. The story of the game has you save a guy, which wasn't terribly frequent for its time.
There's the Dead of Alive case too, controversial on a few aspects, but very clearly declared a female character its protagonist back when the original game had only 3 of them, leading up to DoA5 which now has perfect gender parity, if you exclude the 3 guests characters, two of which are female, having girls outnumber guys by 1 (I'm not counting Alpha-152, that's an "it").
Street Fighter spin-off also have an interesting, if recent history on handling the cast: Udon comics release 3 spin-off comic mini-series focusing on female characters (Chun-Li, Sakura and Ibuki) before they ever bothered to do so with a male (they'll soon release one based on Gouki/Akuma). It's arguable that the main comic already covers the male cast so that those characters don't need a mini-series, but a whole lot of it ended up revolving around Cammy.
And then there's that Legend of Chun-Li movie, which felt pretty unprecedented as game movie spin-offs go, regardless of its many issues - someone bothered and released it.
I'm yet to see Wreck-it Ralph, but from the little I've read to avoid spoilers, it seems they tried to address that too when comparing older games like the title character's with more modern stuff, like the movie's own "Hero's Duty".
I don't know, this is just stuff that comes to mind on the topic, I can hardly claim to have a clear perspective on the issue, but if anything, I've left some ideas, brain farts and examples to be argued with and/or improved upon.