Thanks Sean - yeah, I was trying to keep my budget comfortably below $1,000.
You shouldn't have a problem with that.
PCPartPicker part list:
http://pcpartpicker.com/p/2hQKl
CPU: AMD FX-6300 3.5GHz 6-Core Processor ($109.99 @ Newegg)
Motherboard: Gigabyte GA-970A-DS3P ATX AM3+ Motherboard ($79.99 @ Newegg)
Memory: G.Skill Ripjaws Series 8GB (2 x 4GB) DDR3-1600 Memory ($49.99 @ Newegg)
Storage: Western Digital Caviar Blue 1TB 3.5" 7200RPM Internal Hard Drive ($59.98 @ OutletPC)
Video Card: EVGA GeForce GTX 760 2GB Video Card ($249.95 @ Amazon)
Case: NZXT Source 210 Elite (Black) ATX Mid Tower Case ($42.98 @ Amazon)
Power Supply: XFX 550W 80+ Bronze Certified ATX Power Supply ($59.99 @ NCIX US)
Total: $652.87
That's all without an operating system, monitor, keyboard/mouse and whatever other peripherals you might want. Not sure if you have any of these already(or access to a copy of Windows). Even if you have none of these things, you should still be able to keep it under $1000 quite easily.
Should be a good basis to work off of. That setup right there would do you fine, but you might want a different case or something and the motherboard only supports a single GPU, which means you couldn't add a 2nd GTX760 down the line or anything, which may or may not interest you(I don't think that's a big deal, but that's just me).