"Sure it did"
EDIT: To further clarify. The incursions began occuring because universes vanished, the 'web' that holds them together began to contract and caused universes to collide. They had to kill enough MM's (and thus enough universes) to cause a contraction large enough to start the incursions. If MM's universes don't die, then killing him wouldn't cause anything.
The problem with that interpretation is that then there is no point to killing the beyonders or the MMs, since, one way or the other, everything will end in 25 years, max, and the only recourse will be whatever meager existence they can manage in white space, chilling with mr. atomic underpants until TOAA gets off his fat ass and recreates everything.
Which is why i read the "sure it did" as "things have changed, you just havent done enough yet to see the cascading effects". Red incursions.
Plus, as reed said in early N.A., what caused the initial chain reaction wasnt several universes disappearing at once, but one. Blue incursions.
Then there's all the hoopla about how they were shanked-dead but not dead-dead, and so their corpses could still be used as IEDs and gaaahblfug
Quality wise it plummeted right after issue 9.
Id pay good money to see Hick's face when he found out that Tony's brain cancer saved the day.
No wonder one of the first things he did when he got control of U. Reed again was kill that thing.