Something I've been thinking about (new trailer related):
We've seen weird skin lesions(tumors?/whatever) on the chest of that one guy on the table. And we've seen those skull soldiers with a weird focus on their boobs. What if those are experiments that turn men into women? I don't want to go the quiet is chico route but I think that may be reason we will be "ashamed of our words and deeds". Quiet used to be a man. The prototype so to speak.
or maybe Kojima just likes boobs.
or maybe Kojima just likes boobs.