Funny question. Is David Wise now full-time staff at Retro? What are the possibilities of him helping to compose another Metroid? :O
He's independent, but I'd love to see him return to their future projects. Though speaking of which, if she were still composing, I actually wouldn't have minded seeing what Eveline Fischer would have done for a Metroid soundtrack...
As for Hunters? I'm not really sure why it exists, but I'm glad it does. I think it's a pretty good game, even if it is one of the weaker Metroid games.
Hunters was a massive waste of potential. It was impressively functional as a tech demo on the DS, but its engine would have been capable of delivering something roughly equivalent to one of the Prime games if in the hands of more capable designers.
And considering Uprising worked relatively well, I wonder if perhaps in hindsight it might have been a better idea to offer an optional third-person mode as well; dropping Prime from the title so as to allow the game to exist as an entirely separate spinoff. Having a 'Metroid Hunters' series fill a similar niche to Mario Kart, Touch Kirby / ____ Curse or Hyrule Warriors might have had some positive effect on the overall franchise.