Some impressions from me:
-MyCareer is straight up cringe-worthy this year, even more so than the last two years. Why is it called "MyCareer" when you're actually playing as someone else, who just happens to be called "Frequency Vibrations." FREQUENCY VIBRATIONS. Let that sink in. Not only that, but the dialogue seems like it was written by a 12 year-old, and I'm not exaggerating. Almost all of the actors look weird (Freq's mom, his girlfriend), some of the cutscenes go on WAY too long to the point where it's awkward, and the main character that you play as has the same exact personality as the cheesy player you've been playing as for the past few years. They label this as a "Spike Lee Joint" but I'm positive he just came up with the basic plot and left all the writing and dialogue to 2K. I see no jump in quality story-wise from the last few games.
-The soundtrack is definitely the best in recent years, but just like the last few games, you can barely hear it. When the game starts up, the 2KTV preview will automatically play and interrupt the music. The loading screens for MyCareer and other modes just have generic 2K music. What's the point of having a 50-track soundtrack when you can barely listen to any of the songs?
-As for gameplay, blocks are just way too easy and come up way too often. I actually liked it at first because I thought it was too hard to block in previous games, but here it's like you always have a 70%ish chance to black someone as long as you're close. Especially when you're chasing someone down on the fast break, as long as you're close to them, you WILL block that dunk 9/10 times, from what I've played. It's comical.
-This isn't really a negative, but I'm not really liking the changed controls. I probably just haven't gotten used to them, but I always seem to pass to the wrong person whenever I press the high pass or bounce pass button, and it ends up in a turnover. The previous way to do bounce passes felt so much smoother imo. Another thing that I absolutely hate is how you do substitutions - with the right stick instead of the traditional way with the d-pad. What were they thinking?! It seems like one of those random changes they make just to be different from last year. It takes way too long for the names to show up and makes on-the-fly substitution pretty much impossible.
-I've only played two online games but they were both laggy as hell. And I'm still missing freethrows with players who have an 80+ free throw rating by just barely missing the center of the shot meter, while I cash them in with low-rated centers. Just like in 2K15. This is a killer during close games and it's annoying. I've seen it happen to my opponents too (Dude missed both free throws with Steph Curry and made both with one of the power forwards.)
-Presentation-wise, the game is phenomenal. This is why 2K is still around. Seeing the little things like Steph and Kevin Durant take their mouth pieces off during timeouts, specific celebrations, all the different animations that look just like how they appear on TV, and the pre and post game stuff as well.
-I don't know if anyone mentioned this yet, but one of the most ridiculous things in this game is the "BUY WINS" option for the Play Online ranked mode. You can literally spend VC (aka real money if you want it fast) to rank up quickly. It's disgusting and I can't believe there isn't a separate thread on it here. VC continues to plague this series.
All in all though, I think it's better than the last two current-gen games. There's just still too many things they haven't fixed yet and things they changed for the worse.