One of Brees' young fans is Micah Roshell, 12, who is battling Hodgkin's lymphoma.
Micah's mother, Val, says she recalls the January day Brees and "a very pregnant Brittany" walked into Micah's hospital room and granted his wish to see his hero.
"Micah was very depressed because he knew his time was coming to an end," his mother says. "But when Drew came in with Brittany, I started screaming, 'Drew Brees is here!'
"Micah woke up and started talking to Drew. They began to play the Wii games. The two of them were inseparable."
Brees wore a mask because Micah's immune system was so weak. Micah won every game.
"After his visit, my son began to do what Drew Brees does every Sunday: He continues to fight and win," Roshell says. "Three weeks ago, we went to the clinic, and nobody recognized Micah. He looked that different."
Says Micah, "Drew told me to keep fighting."
Micah is healthy enough to have a November bone marrow transplant.
"That is awesome," Brees says. "Sometimes, the best treatment for some of these kids is not the medicine. It's the ability to put a smile on their face, to give them hope in a different way."