CM nightlies are a good way to go, just don't expect much functionality from the S-Pen. A lot of the S-Pen features are directly tied into TouchWiz and have yet to be replicated outside of it, but you can still use the pen for input purposes though. Multi-window is out as well, since its a TouchWiz thing too. There is a note app on the Play Market that is supposed to be comparable to S-Note. I've never tried it but it is mentioned a time or two in the AOSP ROM section. Also, there are tons of voice-enabled search and control apps similar to S-Voice.
There are issues with AOSP on the Note 2 though, such as bluetooth audio for calls is rather poor, the loudspeaker volume is very low, and GPS can be "flaky" at times. I suggest checking out
XDA-Developers for ROMs and such. There are modified TW ROMs that are nice, such as Jelly Beans and CleanROM, that give you full functionality while also giving you the option to customize and enhance your experience.
One last thing, you can still use the Note's special features with other launchers.
EDIT: Go Launcher has become a massive bloated pile of bile. I suggest trying something like Apex or Nova Launcher. Perhaps even ADW Launcher. I'm fairly certain all of those support Go Launcher's themes.