I'm sure this has been brought up, so I apologize in advance, but... why no full 720p display with softkeys rather than hardware keys? One thing I love about my Nexus is how, when watching widescreen videos on it, the softkeys disappear to let me utilize the full 720p 16:9 display area. With what Samsung has gone with here, you're forever stuck with those thin black bars and slightly downscaled HD video.
Also, their TouchWiz GUI looks pretty bad compared to vanilla ICS. But no surprises there, I guess.
Other than that the phone looks pretty sweet, but it won't be the one to make me feel the need to upgrade from my Nexus.