You can see that this time you can follow the trailer of the "boss" and the removal of areas, which is a big difference to all the other games. Also some things they said (like hiding) seems that it could make the hunts easier. You now have damages shown, so you kinda know after a while how much HP the monster has.
You can get resources automatically instead of waiting for the animation to run out.
I am in no way saying that it wont be a good game. All I am saying is, from what we heard and saw, that it might be easier than most other titles and closer to Frontier/MHO than to 1-4.
Btw. Trillion is 5,59 at Bundlestars:
https://www.bundlestars.com/en/game/trillion-god-of-destruction