Oh for fucks sake, it's a film specifically geared to be offensive humor, created by the man who kick started a heap of offensive cartoon comedies.
Usually I try to be levelheaded about things like this but man, this overly sensitive outlook on everything is driving me mad. Humor about a topic doesn't mean the creators intend to be "transphobic" or overtly "racist."
People need to accept that certain films, websites, shows or games simply aren't for them if they are so easily "triggered" or offended by simple parody, humor or the use of a particular word.
I'm not defending hatred or bias, but it's clear there is none to be found in a movie about a fucking stoner teddy bear that talks.
This shit needs to stop. This over-sensitivity to every topic is ruining parody. These people demand the world be a serious, organized place with certain words completely omitted from speech so as to not offend a single party in any way.
That's not going to happen and it shouldn't.
TL;DR: Loosen the fuck up, people.