It depends on the Doctor. There are several that you will utilize on the journey. In all, (so far) I have 3 professionals that I see. A GP, Therapist and Endocrinologist.
The Endocrinologist is wonderful and treats me like he would any other female patient, his staff do too. (I guess they would be used to it) My GP is a very friendly, very respectful man who listens to my frustrations and offers nothing but firm medical advice, support and encouragement, the way he speaks and interacts with me makes me feel as if he is talking to a woman.
The Therapist is where I have the most issues, Although she did give me the go-ahead I needed to start hormone replacement therapy, she made me feel as if I was being interrogated, tested and determined whether or not I was a candidate for HRT. There's a scene in Transamerica that nails this completely.
'Do you consider yourself a happy person?'
'Yes... I mean no... I mean, I will be..'