Yes, but those are much harder to handle, if you're not switching to a bunch of new characters, like JoJo's Bizarre Adventure for instance. You spend time getting to know a group of people, and then they suddenly become strangers to you again. It's very difficult to write a story that way, just look at how much effort George R.R. Martin went to to avoid having a timeskip in his books.
Also, when did your tag change?
Having just come from watching The Wind Rises, I was thinking along the lines of showing different stages in someone's life, for example. It reinforces, rather than dissipates, the character's ideals, traits, inspirations, or motivations. Of course, Mr. Miyazaki is rather more talented than the average anime tv director, so there's that to take into account.
Icarus-Heika-sama~ helped out a week or two ago