In a huge suit of armour that was continually destroyed and replenished? And MCU Hulk is nowhere near as powerful as Man of Steel Supes. In The Avengers Hulk gets knocked down for a few minutes by a group of aliens' concertedly firing on him, while pretty much nothing stops Superman in Man of Steel.
He must be using Kryptonite though, as in that newest trailer when Supes tries to punch him and he blocks it, Clark looks visibly shocked.
EDIT - not trying to shit on the movie or anything, and I'm sure with Snyder directing it will have good action; I'm just curious how they're going to frame this as anything approaching a fair fight.