That's true without any other boosts, but with High rank you should pretty much always have a Powercharm and Powertalon, along with eating for attack and, at minimum, Mega Demondrugs. Once you reach that you end up with the first set being slightly stronger against .45+ hitzones while having the bonus of Razor Sharp. Not going to bother with situations where Weakness Exploit doesn't activate since the second set still wins there easily.
First set: (180 + 6 (charm) + 9 (talon) + 7 (Attack L meal) +7 (Drugs)) * (1 + (0.90 * 0.40)) = 284.24
Second set: (200 + 6 (charm) + 9 (talon) + 7 (Attack L meal) +7 (Drugs)) * (1 + (0.90 * 0.40)) = 280.525
So basically if the head of the target is .45+ then the first set is somewhat better. As a result, I'd actually favour the first set over the second, as for most monsters you're going to be triggering Weakness Exploit naturally while doing your hammer thing.