Some thoughts about the game:
My brother pre-ordered this game (360), he likes cyberpunk and liked the first Deus Ex quite a lot (and, AFAIK, never managed to finish DE:IW). Me, i wasn't really interested, didn't pay attention to any info etc and i haven't played the original Deus Ex. But i did try the game... and got hooked. Very good.
Sneaking around looking for alternative routes or trying to figure how to dispatch guards without killing them is a lot of fun (trying to do a pacifist first playthrough). This game feels like a puzzle game rather than RPG or action game... But then it is a mixture of genres. Boss fights (currently finished only one boss, i'm in Sanghai) are shit though, luckily i have a rocket launcher (which takes a lot of valuable inventory space).
Augmentations are a fun way to develop a character, each one gives something tangible (well, mostly anyway, augmentation upgrades just make them more powerful but there ain't many of these). Some do, however, feel redutant and/or marginal, like hacking analyzing addons.
I like the graphical style though lack of motion blur is a bit annoying. I like subtle motion blur like Reach and Crysis 2 have. Also, character models and NPC animations feel a bit dated/stiff/repetive. But those are minor things, the game's gameplay is excellent.
I've notice that lack of ammo is often criticised but if ammo were plentiful, people would stick to one weapon and a shooting. This way one needs to explore (good way to get more ammo), plan and try different weapons. If this were pure shooter, lack of ammo wouldn't be good, i always hated how Halo 2 and 3 didn't have much SMG (and generally human weapon) ammo despite it being basic stuff.
As for the story and themes... I haven't made my mind up about the story yet as i'm in the middle of the game but it feels good... a bit of mystery in it. Combined with gameplay, it works. Exploration/puzzles and mystery get along well. The themes are far more interesting for me than the story, as i'm an advocate of transhumanism and very interested in it. Though i'd rather have it done through genetic engineering than cybernetic prosthethics and modifications. Genetic engineering happens to be hereditary and any future generations get use of it. Hopefully for good.
I've seen only two glitches so far, some hooker was standing midair and i pulled a big trashbin through a wall but then i rarely/never observer any bugs or glitches even in games that are (supposedly) very buggy like Fallout New Vegas.
Will post some more impressions later, maybe.