A person infected with LPV comes out of the fever in a highly dangerous state. The victim will display fierce aggression and bloodlust. Their communication degrades into grunts, growls and hisses. They will make great efforts to flee the company of humans and complete their transformation in a more secluded area, such as a forest, a sewer or an abandoned structure.
The physiological transformation to werewolf begins approximately one week after infection, as the virus essentially takes over the body's process of cellular differentiation. The viral DNA selectively turns on and off certain parts of the human genome based on the final design of the organism. Bone growth occurs at the skull and along the spinal column. The torso becomes elongated and the bones and musculature of the pelvic and shoulder girdle expand. Coarse hair will grow all over the victim's body. There are numerous other significant physical changes: hands become paws, fingernails become claws, the jaws and teeth take on a lupine appearance and the eyes develop a yellow hue and the pupils become narrow.
The full transformation from human to werewolf takes up to six weeks to complete. At the end of the process, the werewolf will walk and run on all fours. Werewolves can continue to grow during the first years after transformation, especially when the food supply is abundant.