2 and 10 point is white balance, I'm talking about color space where you can calibrate red, green, blue, yellow, cyan and magenta.
I have switched to auto for both regular and HDR mode for now, don't notice a drastic change in either mode, but obviously this still doesn't answer my question.
And yes, there is an entirely different set of picture settings for HDR (the one cranks up backlight to 20 by default).
Related question: For my Xbox One S, I'm using 4K output at 10bit, color space limited. Should I choose RGB for this? My PS4 Pro defaults to RGB (at least in dashboard) on auto setting.