In regard to criticism of writing and animation, I've found it to be wildly inconsistent. You can go long stretches where everything's fine, and then a really bad line, or animation, or line reading comes along.
The only thing that's consistently bad in terms of animation is my default Scott Ryder's eyes. They are incredibly weird and creepy. Human eyes just don't look like that. Also his arms and hands and the way they move are pretty terrible too.
As for the writing, this game obviously had quite a few writers, and some are ok/good and some are awful. That line about 'his heart broke just before it exploded' has to be one of the worst I've ever heard. It's spectacularly bad. Worse than 'my face is tired'.
But I played a lot over the weekend and I barely noticed anything really egregious. I've most been pretty lucky with bugs and glitches too. I think I've only had one animation glitch so far in 20 hours on PC. The bug/glitch videos definitely don't create an accurate portrayal of the game. People obviously go out of their way to break the game and when they do they milk it for all it's worth.