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[JC Sera]

This is the post I've been waiting for; thanks for the input, Hackworth.

What kind of environment do you think would stress these ancient viruses enough to develop hundreds (and thousands) of genes, versus the simple genetic composition of modern viruses?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083134/#__sec4title
Heres a couple of examples of what that large genome codes for

also I was wrong giant/mimiviruses being benign to humans
they have been linked to pneumonia in humans, apparently giant-virus infected amoeba (which can cause pneumonia) are resistant to disinfectant and are found everywhere, and can be pathogenic

 

[Darg]

just in time for September 23...

This is going to give them more ammunition isn't it?.....

 

[Az987]

Screw it, if all these viruses are in the ice it's only a matter of time until we wake them up anyway. Inject me with it so I can be immune. I'm pretty sure that's how that works.

 

[Hackworth]

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083134/#__sec4title
Heres a couple of examples of what that large genome codes for

Yo, thanks for this. It's been so long since I did viral stuff I didn't know where to start looking.

also I was wrong giant/mimiviruses being benign to humans
they have been linked to pneumonia in humans, apparently giant-virus infected amoeba (which can cause pneumonia) are resistant to disinfectant and are found everywhere, and can be pathogenic

Aw shit.
If that's an inherent resistance because of structure and not a relatively recently evolved one this reanimation could get dodgy.
At least they'll probably be working on it in an isolated high-biosecurity lab so it'll probably be fine.

 

[Mammoth Jones]

 

[Sgt.Pepper]

fuck I remember some bollywood movie about a virus from a frozenland

 

[Spladam]

If it needs to. I will begin my name change processing early next month, then be defecting/emigrating asap.

I'm thinking KGB.

You look deadly, but's that's probably just your OLD identity.

I sure hope this is not some Leon Kennedy with one pistol kind of thing. Try to bring both RED and GREEN herbs with you, don't count on them being on site.

 

[evilromero]

X-Files kind of did this.

https://en.wikipedia.org/wiki/Ice_(The_X-Files)

The Thing?

 

[Spladam]

Sure wish I could Un-see this. It's burned into by brain now.

 

[Verendus]

This is like one of those M. Night Shyamalan movies.

 

[gabbo]

What is going on here?

 

[BLOODED_hands]

Please let this virus cure the common cold.... That also turns people into zombies. I've seen too many movies to know what's going to happen next.

 

[AP90]

That's the beginning of a disaster movie if I've ever read one.

This. But if they know how it interacts/works, they will have an idea to know how to counter it.

 

[~Kinggi~]

What is going on here?

ITS THE BLACK OIL, MANG THE BLACK OIL

 

[Camwi]

I for one welcome our new viral overlords.

 

[Yleyana]

I'm thinking KGB.

You look deadly, but's that's probably just your OLD identity.

I sure hope this is not some Leon Kennedy with one pistol kind of thing. Try to bring both RED and GREEN herbs with you, don't count on them being on site.

I'm dead serious. Some things get more dangerous with time, some less.

 

[Sho_Nuff82]

Big scare tactics.

We actually don't know what's in the ice, so caution should always be advised.

 

[-COOLIO-]

gg

 

[Spladam]

We actually don't know what's in the ice, so caution should always be advised.

What's in the ice? I'm thinking some 90 million year old microbe that living creatures no longer have ant-bodies for and is air borne. It's why Hydraulic Fracturing rigs pump hundreds of gallons of high power antibiotics and sterilizing agents (for real) into the solution, to kill possible microbes that might have been trapped in the deep layer rocks.

 

[TAJ]

A good chunk of the scientific community reminds me of Bart Simpson touching the cupcake.

 

[Prototype Viktor]

They should put it in a animal right away for it to replicate and have more to study. Such pansy's

 

[lazygecko]

A good chunk of the scientific community reminds me of Bart Simpson touching the cupcake.

Prometheus vindicated.

 

[JC Sera]

What's in the ice? I'm thinking some 90 million year old microbe that living creatures no longer have ant-bodies for and is air borne. It's why Hydraulic Fracturing rigs pump hundreds of gallons of high power antibiotics and sterilizing agents (for real) into the solution, to kill possible microbes that might have been trapped in the deep layer rocks.

for fucks sake
1) Your antibodies are not inherited. I repeat they are not inherited.
2) Your antibodies are all randomly generated. The human *adaptive immune system is one whole gambit of "I will randomly generate one antibody that will bind to one antigen that is a part of a pathogen" and plays the game by creating millions of outputs
3) You can lose immunity to an organism you are immune time in your own life time. Its natural.
4) When it comes to viruses they are really niche in hosts, a couple of centuries of genetic drift alone can potentially put them out of their game

people really need to stop going microbe=pathogen
or even opportunistic pathogen = true pathogen
the only microbes that are obligate pathogens as an entire kingdom are viruses and antibiotics wouldn't even work against those.

Those microbes are important, if we tried to wipe out every microbe we find in a weird environment, we wouldn't have taq for DNA polymerization today.

 

[Ayt]

A good chunk of the scientific community reminds me of Bart Simpson touching the cupcake.

It isn't their fault these things are being unearthed. Would you rather industry moves in without having any idea of what they might be dealing with?

 

[Spladam]

for fucks sake
1) Your antibodies are not inherited. I repeat they are not inherited.
2) Your antibodies are all randomly generated. The human immune system is one whole gambit of "I will randomly generate one antibody that will bind to one antigen that is a part of a pathogen" and plays the game by creating millions of outputs
3) You can lose immunity to an organism you are immune time in your own life time. Its natural.
4) When it comes to viruses they are really niche in hosts, a couple of centuries of genetic drift alone can potentially put them out of their game

people really need to stop going microbe=pathogen
or even opportunistic pathogen = true pathogen
the only microbes that are obligate pathogens as an entire kingdom are viruses and antibiotics wouldn't even work against those.

Those microbes are important, if we tried to wipe out every microbe we find in a weird environment, we wouldn't have taq for DNA polymerization today.

Ok, relax JC, I have no hate for the pathogens. Thanks for all the info though.

 

[Ianan]

Holy shit I've literally just finished watching The Thing and then I read about this.

 

[JC Sera]

Ok, relax JC, I have no hate for the pathogens. Thanks for all the info though.

Sorry, its just this is my area of study, and all the paranoia & misinformation fucks us over a lot. People are worried about scientists "playing god" with spanish flu & ancient microbes
when the real problems are at home and mundane such as MDR-TB & MDR-gonorrhoea is constantly on the rise, and antibiotics are still over prescribed.

Oh and anti-vaxxers, with first cases of polio in decades in eradicated areas are cropping up over the last two years.
Also whooping cough.

 

[Seductivpancakes]

Sorry, its just this is my area of study, and all the paranoia & misinformation fucks us over a lot. People are worried about scientists "playing god" with spanish flu & ancient microbes
when the real problems are at home and mundane such as MDR-TB & MDR-gonorrhoea is constantly on the rise, and antibiotics are still over prescribed.

Oh and anti-vaxxers, with first cases of polio in decades in eradicated areas are cropping up over the last two years.
Also whooping cough.

I'm pretty sure most people on this thread is kidding. I appreciate you dropping science tho.

This thread did remind me of Contagion and what a fantastic film it is.

 

[A More Normal Bird]

Water will keep running
Rivers will turn
Water will keep running
Rivers will turn

 

[Spladam]

Water will keep running
Rivers will turn
Water will keep running
Rivers will turn

For the sake of the reference:

https://www.youtube.com/watch?v=qzfg8ziVInI

So how can I ever find
What I’m looking for
When it’s been frozen
Stuck at the horizon

The wind blows from north to south
But I’m still where I was
Keep taking some shirts on
And taking them off

Peeling off the layers
Peeling it off
Peeling off the layers
Peeling it off

I wish I could find a cure
And to know my disease
But like nothing is certain
The circle will form a line

 

[TheOMan]

That's the beginning of a disaster movie if I've ever read one.

Wonder how long it will take until we lose contact to the research base.

I'm laughing with fear

 

[Cipherr]

I have seen this episode of Stargate SG1.


Stop fucking with stuff.

 

[AcademicSaucer]

Cant they just launch that thing with a soyuz towards the sun ?

 

[WonkyPanda]

It's been a while since I focused on microorganisms but I'll give this a shot.

Natural selection can act as a simplifier: as I understand it, viruses are (basically) sections of larger organisms (eg RNA transcribers from inside a cell) that broke off and found a parasitic niche.
Viruses with less genes will replicate more quickly than larger ones, and may therefore be better able to hijack targeted cells (and may produce more descendants with less resources, allowing them to overwhelm more cells).

Bacteria are similar: in environments with few stresses, bacterial selection tends towards very simple and quick replicators. You get pressure to hold onto plasmids and activate secondary DNA when stresses kick in.

This was my thought as well. Isn't it telling that viruses over time have been selected to be simpler?

 

[Livingskeletons]

"I thought you'd post this link OP. You were the only one who could have gotten to that blood, we'll do you last"

 

[titiklabingapat]

I saw on a documentary once that viruses probably evolved concurrently with single celled organism and that one or the other spawned or helped spawned the other,especially complex cells. Of course, that is just one theory of viral origins but the existence of larger and complex viruses definitely supports this theory.

Viruses are fascinating to me. Most of them cannot multiply without a host cell and apparently many of our genes and many living beings' genes were given to us by viruses. We are in, essence, are a combo of virus genes from my basic understanding of it.

 

[ItIsOkBro]

I'm laughing with fear

What does that even sound like

 

[BananaPancake]

Fascinating! They always find such interesting things in permafrost.

Thanks for sharing OP.

 

[shoreu]

No way! Ha ha. The lizard people do not exist. But if we did exist, they would certainly be acting in your best interest and would alleviate your fears over what is clearly something innocuous.

Kill the demon.

 

[Hypron]

The next supposed doomsday.

So the world will end on my birthday. Thanks for the birthday gift, god.

 

[Always-honest]

Smart thinking.

But this is how it will end, isn't it?..

 

[Mermandala]

What does that even sound like

Like almost all of the characters in Bloodborne.

 

[Cizeta-Moroder]

UNLESS, it being a virus, it may have been SO potent it killed EVERYTHING and died out along with the hosts. Until now!

So it's a reaper virus

 

[JMDSO]

The EXACT thing I thought of when I saw the title.

Also helps that we just started a re-watch this past week.

 

[SliceSabre]

An old virus found frozen in Siberia.

I've seen this disaster movie and X-files episode before.

 

[Mobius 1]

Not this shit again

 

[Prototype Viktor]

Horrible timing. This Week In Virology ep already came out like 4 days ago. Now the wait for them to talk about it