Fairly certain The Genesis uses the same midi sound set the rest of the game uses. It's just that meguro adds an intentional echo to the mix.
I don't mind the genesis, but it's so quiet for so much of it that I actually couldn't hear any of it. Also, the big sweeping remix of Reach Out at the end isn't timed with anything, so you could hear it before you've finished the fight and then it's right back into ominous. The song just sounds out of place after the high energy of Mist. If it were up to me, I would have switched them around.