Well, let's not pretend that voicing a mascot character in an anime is Oscar worthy and dubbing a video game is community theater. There's certainly a difference in prominence, but without taking anything away from Otani (she's a legend), I don't think it's fair to imply there's a comically large difference in the acting chops involved.
I was referring to
It's a pretty star-studded cast of voice actors/actresses on the Japanese side
not the Pikachu lady.