I think I'm pretty close to being finished with this game already, which is unfortunate.
Since I've expanded my fleet and opened airports across the pond, my profits have actually gone down and the amount of work I have to do has gone up. Perhaps I'm not playing the "right way", but it feels like too much of a chore to come back to it.
Maybe if there was more of a reason to play... perhaps the chance to get a unique character/pilot, or plane decal or something, but all there is is more bucks and more coins, and ultimately it doesn't amount to much of anything.
Fun ride while it lasted and I played the hell out of it the past few days, but shame it didn't last a week for me. It was cool that there was much more playtime early on compared to Tiny Tower, but that pace never really cooled off, which led to the overload.
I'll still play the next NB game though.
If you follow the plane upgrade arms race, you'll need to feed bigger planes with smaller planes, and the work can go up, as you need to manage layovers etc.
Or, you can keep relatively small planes (Mohawk is good) and have longer end to end journeys. Smaller capacity means easier to fill, and slower means more time between attention. A flight between tokyo-LA is a couple of hours. You might need to wait a couple of job refreshes, but no micro management needed unless you want it.