Uh... I'm left handed too and the fact that this is probably the first true amibdextrous controller is one thing that really excites me.
Just to throw in my .02:
I like it. I really, really like it. It took me about 10 minutes to get over the WTF element, and another 15 to get past my whole 'how do you play 'x' on that' train of thought, but once I started thinking about the possibility, and the potential, I got extremely excited. This is in very sharp contrast to the DS, where I was thinking "okay, well... I guess that could be okay." I'm thinking now that this very much could be a Revolution as Nintendo intended.
To get on a little soap box, I think this is the BEST thing Nintendo could have done at this point. The last generation, despite a few good moves showed a very downward trend in what Nintendo had been doing; 3rd parties would slough off a sloppy, 2 month late port of a game, it wouldn't sell, and 3rd parties would withdraw support. Nintendo's significance in the console race was diminishing and diminishing. Had they made GC II, this diminishing returns would've continued and I seriously think Nintendo as a console maker would be done after next gen.
Now, Nintendo is going in a very bold direction... yeah games as we know may not fly on the Rev, but Nintendo KNOWS that. They want different ways of experiencing things we're already familiar with, and I honestly want to see if they succeed. Yeah... 3rd parties won't be able to port their established games as easily or willingly anymore... but let's be frank. 3rd party support right now, and for the past year has been HORRIBLE for the GC. Sure, 3rd parties will have to try a little harder now, and make some innovative changes in their franchises, old or new, but if they pull it off, it will succeed in the long run.
A lot of those criticizing Nintendo would've criticized Nintendo anyhow. If Nintendo busted out a GC II with increased graphic capability and HD support to head on with the PS3, they would've called it out as too little too late, and that only N-fans would support this new system. If they added a simple gyro, they would've been calling out a gimmick. With this, a brand new way of interacting, they're saying it's stupid, not traditional, and completely off the wall (which kinda confuses me, especially with Drinky's steadfast embrace of all things traditional, yet his complete dismissal of anything resembling nostalgia, but that's for another time) so the reaction is pretty much what I expected. However what I'm getting from a lot of other people, surprisingly, is a genuine interest, and intrigue on how this is gonna work... something that I didn't see during the DS's conception.
What Nintendo needs to do now is let the idea of the controller sit. They need to go ahead and explain what the Wi-fi will be like (I guess in October) and now, need to woo the 3rd parties... show them how it can work and let them do their things, (especially people like Miziguchi and Naka.) They need to explain later on the 'shell' idea, and how it can still be a traditional controller for those 3rd parties that just want to simply port. Then, E3 needs to be amazing. They need to show Mario Rev using the controller, and show people WHY this controller will work. They need to do this with an FPS too (Metroid I guess would work) and simply show the world the uses of this.
I have my money plopped down on my 360, and I am looking forward to that, but it's more of a "huh, next gen's here already? Okay, I'll pick up 360... I guess PD0 and Ghost Recon look cool" reaction. For the Revolution, I am really excited to see the new innovations that can come of this. An excitement I haven't felt in a long long time.