Not necessarily; Microsoft has had a long-standing relationship with not only Bethesda but also iD Software. It was the OG Xbox that got a DOOM 3 port back in the day, after all, and Microsoft's investment into Bethesda during that era is what allowed Morrowind to be made (and for Zenimax to be formed).
And that was without actually acquiring them to make those investments. Honestly, it's more or less semantics at the end of the day; both companies have made acquisitions and both have also encouraged "organic growth" with internal studios. It is a bit of a chuckle though on that note considering there isn't a Sony studio outside of maybe Polyphony and 989 Studios (that I can recall) who is 100% built from the ground-up in-house, whereas IIRC Turn 10 and even 343i were built up in-house, The Initiative also join that list on Microsoft's side.
But like was said ultimately this shouldn't matter, as both companies have done this and will continue to. The people trying to move the goalposts in ways like "yes but this company never acquired a publishing arm!" are acting weird. If said company had the financial capacity to purchase that publisher, they would have. That's how capitalism works. In terms of being for or against acquisitions, I don't root for or against it, I just like to view it in terms of market realities. The truth is, almost any company Sony were to consider acquiring, a company like Microsoft would also likely be looking at, and the latter can easily outbid the former to win the acquisition.
Even the usual talking point of "but it's hard for American companies to buy Japanese ones" doesn't really work: for starters, that's only mainly true for companies in industries Japan consider of critical importance (military, defense, medical, civil engineering, finance, law firm etc.), which most gaming companies don't fall under the definition of. Secondly, Microsoft have already shown they can acquire such a company now that they own Tango Gameworks. Thirdly, if Sony were to make such a gaming purchase they would likely do it under the PlayStation division which now operates out of California. So they would face similar extra regs to clear the way a company like Microsoft would.
But really it's the money side of the argument why gunning after those type of publishers would end up cost-prohibitive for Sony; keeping in mind they'd probably be looking at upwards 2x their valuation as payment to acquire them, and I wouldn't want to see Sony go into a ton of loan-borrowing the way Disney did, to make these acquisitions, considering Disney ain't exactly sitting in the best of condition these days.