You can't nuke your own cities. If you're playing a game with just yourself (no AI enemies) he'll only fly around your territory so you need to click the areas that aren't cities to nuke them. As for the interface, leftclick selects and rightclick changes modes. Nuke silos start off in air defense mode and need to be switched over to ICBM to fire.Goddamn Defcon tutorial doesn't work. I can sort of work the game out but not well enough to nuke Santa. Damnit.