Depends on how you execute said streamlining. Working through poorly designed aspects of the game can be satisfying once you get the hang of it and get through it, but I'm not sure whether that would have been a superior first-time experience compared to a more well paced, well designed version of the same game. There's definitely enjoyment to be found within conquering hardship, but that hardship needs to be intentionally and properly implemented within the game, rather than be the result of poor planning or merely an oversight. I wouldn't want a STALKER game to be dumbed down, as the hardship the game brings with it adds to the bleak, survival-based experience. DayZ's terribly obtuse and messy inventory system on the other hand doesn't really add to the experience and streamlining that aspect wouldn't influence the game negatively. Streamlining aspects of a game would often only harm the game if it takes something away from the core mechanic/experience of said game; it is not inherently a way to dumb down your game.
I understand your point about Skyrim and I agree, but it's not entirely the same situation. Skyrim is a standalone game rather than the remaster of a previous game and it belongs within the RPG genre, two qualities that matter separately. Morrowind was more complex and thorough in practically every aspect of its being and going from such a game to the significantly dumbed down and more repetitive Skyrim is understandably disappointing. One might get the feeling that the franchise is regressing and there isn't really too much we can do about it. Majora's Mask on the other hand is an already existing game, one that is somewhat easily findable and playable (I don't know if it's on the Wii U eshop, but it certainly was on the Wii shop) and the 3DS version is simply a different version of the same game. I certainly did not mind the more inefficient, messy parts of it, but I don't think removing some of those inefficiencies would necessary change the game entirely. The 3DS version is not merely made for people like me, it is also for those who were perhaps too young to have played it in the past or simply never got the chance to do so. And for them, as long as they don't suddenly decide to genuinely dumb down dungeon, side-mission or enemy design, I don't think streamlining some original flaws would strongly hamper the experience.
Aside from that, RPGs are inherently more complex than action adventure games and streamlining the former will change the game significantly more than streamlining the latter. Customization, freedom and combat/dialog/whatever options are somewhat central to your average RPG and those are also generally the aspects that get "streamlined" or dumbed down. I doubt Link losing the speed boost when spinning as a deku scrub is going to change the game's feel entirely, as its more core elements don't seem to be altered too much.
