HadesGigas said:
How many things can you get to follow you at once? I want an army of dead siblings and flies!
As many as you can find it seems. I once had 3 pretty flies, both shooter siblings, the robot, the moneybag and the heart sister at once.
In another run it was 2 pretty flies, 1 attack fly, meatboy, cross and heart sister.
Also for those who have a couple of problems to get through the dungeons, I found the game to get a lot easier to play with Judas (saving the Book of Belial for bosses) and not using the shop a lot. Instead, money gets to beggars who always seem to give the best items before vanishing and sometimes vending machines.
The latter ones and everything else in the arcade can be bombed if you want to save your money and don't care for gambling.
For keys, the golden doors always get the priority with golden chests in arena rooms second. If I got enough keys for golden chests, I take those, too.
Eat any pills that you can find as they tend to give more positive than negative effects (at least for me). The good thing is that the pill effect will be identified and displayed at the top right. The doctors diploma and lucky foot also help immensely there. The foot literally tranformed a "tears down" pill in my inventory into a "tears up" one as soon as I picked it up.
I also try to avoid the devil's offerings except if they cost soul hearts only or if it's either "lord of the pit" or "the nail", but only if I keep at least 3 red hearts afterwards.
Apart from that, the only other little trick I found was that you can lure big chubbs into eating bombs for some nice damage and stopping them right in their tracks.