WAAAAATI remember finding some crazy good shit on fucking Usenet back in the day, black author, wrote a txt about a hacker who used his hacking knowledge to tweak his friend's biotechnology project to create an 0-ring level reboot for the human body, basically allowing him to consciously rewrite the firmware of the body. He infects himself with this synthetic virus, and it's basically IronMan Extremis before Ellis wrote it. Gives himself increased intelligence, perfect body, creates a sexually transmitted version that cures all diseases, and basically starts creating a new race of enhanced human. This is when the secret government gets involved, apparently they've already done this and plan to shut him down, etc. He left it with an open ending, but it could easily be a blockbuster movie.
I must read this. Free GAF-gold upgrade if you can track down the Usenet post.