Actually, Drake being a mass murdered was one of the main reasons Uncharted became a target. It's only now that people are focusing on his neck fetish.
I'm not sure about that. By that metric every shooter would have been made a target.
Like, even the Penny Arcade comic was a commentary on how he'll throw a dude off a cliff without a care in the world.
So it can't have been the body count; again, every game would be a target. I think the root of it always was Nate not seeming like the kind of dude who would kill someone, not that he amasses a large body count.