nope
at least not for DKs, it's already been mathed out which first, fourth and fifth tier talent to take in order to get the most out of the dps and the second, third and fourth tiers are pretty much no brainers depending on spec, a sprint is way better than anything else in the third tier unless something needs to be kitted, but there are classes better at that job than DKs, purgatory is pretty much mandatory for tanks and AMZ for DPS
the only real choice we have is the 90s talent on the sheer fact that they are all absolute shit for pve
I assume there is similar theorycrafting going on for all the other classes, in short as long as there are numbers someone will figure out which numbers are better