Edit: I forgot to mention earlier, you guys should google 'Nero Dante'. The amount of Dante and Nero yaoi is incredible. Like, I'm not fan of that shit bu the dedication is fascinating.
It's tradition - DMC1 started off with the Oedipal subtext between Dante and Trish, and a sizeable portion of 3's fan following was built on the tenuous prospect of fraternal incest; which 4 continued with the immensely popular uncle/nephew relationship between Dante and Nero. It could be argued that DMC2 and DmC's true failing was the lack of any new relatives to pair with Dante - for 5 to have any hope of succeeding, these grave flaws have to be amended.
Notice me, Baajiru-senpai~