I think if my wife and I found that she was carrying a child with down syndrome, I
think we carry to term, but above all I'm glad we live in a country and region where we (and other people) have that choice.
So could Down Syndrome be potentially eradicated from a genetic perspective?
If no Down Syndrome children are ever born, then the chances of those specific genetic abnormalities would eventually lessen to the point of disappearing?
I might be completely misinterpreting the science here.
Down syndrome is not like, say, Huntington's disease (where theoretically if anybody that carried the gene for Huntington's did not have children, the disease would be eradicated, but this is more difficult than it might sound). People who have down syndrome did not inherit the condition from their parents, it's a random event that occurs during pregnancy.
Down syndrome, as we know it, probably cannot be eradicated because most cases of down syndrome (trisomy 21, mosaic down syndrom) are not inherited, "
the chromosomal abnormality occurs as a random event during the formation of reproductive cells in a parent.." A type of condition that can lead to down syndrome (translocation down syndrome) can be inherited, but it's not as common and does not commonly result in down syndrome even if the condition is present.
For the most part, let's say that hypothetically Iceland made abortion illegal next year, then by 2019, the rate of Down syndrome would return to "normal," because it's not an inherited trait. It would be slightly lower as a result of the inherited translocation down syndrome being reduced over the last however many years, but that's not as common of a type of down syndrome. The article write it that "Down syndrome is disappearing." This isn't exactly true. Fetus are likely developing down syndrome at the same rate as any other country or area, but those fetuses are not being brought to term.
Anybody feel free to correct anything I'm wrong about, this is my understanding but I'm not an expert on inheritance, genetics, down syndrome, or anything else for that matter.