I'd like to have it be more like New Vegas hardcore. That sort of thing just puts me off.I can't play Survival due to the limitation on saving. I don't have the certainty that I will be able to sit for a bit and find a bed to survive.
Might be ok with a mod later that toggles some things though, I.E. I'd want to hitch rides on caravans for fast travel or go with Witcher III style signs to travel between. Make it less convenient, but acknowledge this kind of design sort of needs it in some form. Or let me zip across the wasteland in a helicopter or whatever.