Well assuming they want to go the James Bond formula with the MGS games, I'm guessing it won't be a direct sequel to any previous metal gear games but instead it'll be a totally new start storywise (featuring familiar characters + so forth), with maybe some mild references + tie ins to previous games.
Honestly, I'll be disappointed if it does turn out to be a direct sequel to SOL, as Snake Eater really did put closure to the Solid trilogy for me.
Honestly, I'll be disappointed if it does turn out to be a direct sequel to SOL, as Snake Eater really did put closure to the Solid trilogy for me.