Just played through the demo.
I've played Resident Evil 4 and 5 before, 4 being excellent and 5 not really having lasting appeal or any memorable moments.
With 6's demo, I played through Leon's section and played through a lot of Chris's section but had to turn it off. The gameplay just feels wrong and nothing really interesting happened either. I'm very surprised I disliked it as much as I did.
Anyone else having such strongly negative reactions?
Maybe. Yes, I fucking hated the game at first, and even by the time I had half completed it. The demo contains some of the worst sections of the game (not even the worst) IMO. It gets much, much better in some sections though, and your experience may vary wildly depending on how, and in what order you play the game. It's a very different game than RE4 & 5, the focus is mainly on combat and mastering it's intricacies. When RE6 is good, the game it most reminds me of is Vanquish (others have also said this). If you mess around with the demo more you will be able to dig that out of it, however you have to work at it, and it leaves a horrible first impression, and a second, and a third...