Depends. First thing I will say to this is that after this generation, you can throw the historical perspective on controllers for gaming systems out the window. And that's not because Nintendo upended the tea table with motion, or because of Kinect, or Move. Its because several different hardware manufacturers were able to swap controllers in and out of the "center" of their systems without users becoming miffed at the cost proposition.
If a singular controller is no longer required for an entire generation of consoles, then it begs the question whether controllers are becoming more like software in that you could write a new piece and people would gobble it up. If you found a comfortable, standard "LAYOUT" for a controller, and you could change the layout on the fly via touch screens (for example, a screen on the wiimote where the A / B buttons are OR a screen on the nunchuk where certain buttons were, then you would have a proposition that could be swapped in and out, by GAME, and one which would be quite simple to implement: "punch", "kick", "jump", "walk", instead of A / B / X / Y / C. All it takes is the flip of a software switch.
We see it happening already in the phone market. But have we seen it in dedicated gaming systems? Sort of, but not all the way. If Nintendo has chosen a screen to be the center of their control mechanism, with Iwata as the head of their company, you best believe it was for a damn good reason.
Or all these rumors are crap.