Shantae could be nice but all these pixelated games look really ... eww.
I know people like it but personally I'd much rather have high resolution 2D "Sprites" instead of this unnecessary throwback (called nostalgia?) to how games looked back then due to hardware limitations. I simply can not appreciate it the way others do.
But oh well, at least it seems to be a good game and not completely driven by nostalgia so maybe I'll bite.
The way sprites scale makes the initial resolution almost negligible.
Shovel Knight, for example, has really low-resolution sprites that
can scale cleanly to 4K and above. Just as SNES games can look very clean on 4K display devices with the right upscaling equipment.
Admittedly, 2D sprites are created at higher resolution now to give the sprite a little more detail, but they are still relatively small (240x240p).
Risky's Revenge was originally a DS game, but still looks nice when upscaled to your monitor's native res.