"He specifically didn't want to call it No More Heroes 3," says Mountain. "While it's clearly in the same world, it's clearly in the same series, it's clearly connected to the previous games, he doesn't want people to think of it as a direct sequel. He feels it's more the start of a new adventure for Travis, and possibly even a new series for Travis. Again, while it is definitely the same universe, same timeline and everything, it's not really a spinoff but sort of a separate entity. That's why he purposely didn't put a number in it and put 'No More Heroes' at the end, to make sure people could make that specific distinction."
"Another reason he decided to make the title like this -- and I mean not just literally the title, but the game itself also -- is because he wanted to try something new. The previous games were Travis fighting the other assassins; you know, fighting his way up through the rankings. He wanted to do something a bit different from that this time. So, again, while it is the same character, same aesthetic, same general gameplay and everything, it certainly is a different type of game. And he wants everyone to realize right from the get-go that it is a No More Heroes game, but it's a different kind of No More Heroes game."