First off, the HUD in this game is absolute trash. Customization does nothing to save it because the options are so limited.
However, it did get me to disable the minimap completely, along with pretty much everything but the Items in the bottom left and healthbar.
Playing on Death March + no-minimap, it's been an absolute blast so far. My only issue is that getting to the world map takes too many button presses. However, exploration for me has skyrocketed without a mini-map.
And the side-quests, they are fantastic so far. I finally managed to hit level 2 off the completion of one just now. Should make fighting level 6 bears and drowners... somewhat easier.