Just Finished. Overall I liked U2 very slightly more but this game does things much better than 1-3 and things you wouldn't expect from Uncharted. Particular TLOU DNA you find in this game.
Amazing looking. Environmental Detail, Texture Work, Vistas, Animations, Lighting, Particle Effects, and the Digital Acting should make other Devs jealous. I slowly camera panned even near the end. I like never do that in any game. Playing the game feels good (climbing, shooting, traversal). ND has a lot more gameplay tools to throw into the mix like the rope, driving, open encounters, better stealth, sliding sections, and TLOU inspired quite moments and interactions with the environment. These things are small but they freshen up Uncharted's gameplay.
I really liked the more character focused story. I've never been impressed with Uncharted's fairly simple race bad guys to the ancient city plots. There is just much more weight to the story now. Relationships are more than excuses to deliver quips this time around. It helps that there is so much dialogue between characters. The writing is solid and there are strong emotional beats.
My only real negative about this game is the combat encounters and balance. The combat areas are larger and I wanted to swing around to jump dudes, run around to flank guys, and respond to a more dynamic battlefield but never felt like I got the chance. Combat encounters sometimes feel awkward and less fun then they should be. The problem is Nate feels like a bullet magnet. There just isn't enough breathing room when you pop your head out of cover and it feels like 3-4 guys are hitting you all at once. I end up finding the first bit of cover or hanging from a ledge and taking pot shots. Cover breaks easily and the game wants you to move but it does't feel viable to move out of the first bit of safe cover you find. The set pieces aren't as memorable but that is because the game isn't trying to one up the older games in terms of crazy shit happening on screen.
Overall, just a really good game. Uncharted games to me are often well made fun but nothing more. U4 is a smarter and deeper game that the others wanted to be.